Juan C Sáez Selected Research

Connexins

2/2022	Oxidative Stress, Inflammation and Connexin Hemichannels in Muscular Dystrophies.
10/2019	De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia.
9/2019	Direct Intercellular Communications and Cancer: A Snapshot of the Biological Roles of Connexins in Prostate Cancer.
1/2019	Connexins and pannexins in Alzheimer's disease.
8/2018	Involvement of Connexin Hemichannels in the Inflammatory Response of Chronic Diseases.
1/2018	Role of astrocyte connexin hemichannels in cortical spreading depression.
1/2018	Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels.
11/2016	Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal muscles.
10/2016	Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels.
1/2016	Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Juan C Sáez Research Topics

Disease

12	Atrophy 06/2020 - 08/2012
10	Inflammation (Inflammations) 02/2022 - 06/2002
7	Ischemia 07/2015 - 01/2002
6	Muscular Atrophy (Muscle Atrophy) 01/2020 - 08/2012
5	Hypoxia (Hypoxemia) 09/2019 - 02/2010
4	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2021 - 02/2009
3	Neuroinflammatory Diseases 10/2021 - 01/2013
3	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 08/2012
3	Spinal Cord Injuries (Spinal Cord Injury) 08/2015 - 12/2010
3	Inborn Genetic Diseases (Disease, Hereditary) 04/2014 - 06/2005
2	Muscular Dystrophies (Muscular Dystrophy) 02/2022 - 01/2016
2	Epilepsy (Aura) 01/2022 - 01/2018
2	Demyelinating Diseases (Demyelinating Disease) 01/2020 - 01/2017
2	Dysferlinopathy 01/2020 - 01/2016
2	Shock 10/2019 - 09/2012
2	Neoplasms (Cancer) 09/2019 - 06/2007
2	Brain Injuries (Brain Injury) 01/2018 - 01/2015
2	Pathologic Processes 01/2014 - 03/2013
1	Polyps 01/2022
1	Sudden Unexpected Death in Epilepsy 01/2022
1	Drug Resistant Epilepsy 01/2022
1	Parasitic Diseases (Parasitic Disease) 10/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2020
1	Weight Loss (Weight Reduction) 06/2020
1	Diabetes Mellitus 01/2020
1	Atherosclerosis 01/2020
1	Atherosclerotic Plaque (Atheroma) 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Endotoxemia 10/2019
1	Prostatic Neoplasms (Prostate Cancer) 09/2019
1	Fibrosis (Cirrhosis) 09/2019
1	Chronic Renal Insufficiency 09/2019
1	Immediate Hypersensitivity 01/2019
1	Chronic Disease (Chronic Diseases) 08/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Sepsis (Septicemia) 01/2018
1	Channelopathies 01/2018
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2016
1	Wounds and Injuries (Trauma) 07/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2015
1	Keratitis, Ichthyosis, and Deafness (KID) Syndrome 05/2015
1	Keratitis-Ichthyosis-Deafness Syndrome 05/2015
1	Nervous System Diseases (Neurological Disorders) 01/2014

Drug/Important Bio-Agent (IBA)

27	Connexin 43 (Connexin43)IBA 06/2020 - 01/2002
24	ConnexinsIBA 02/2022 - 06/2002
9	Proteins (Proteins, Gene)FDA Link 10/2021 - 06/2007
8	Adenosine Triphosphate (ATP)IBA 02/2021 - 02/2009
8	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 12/2007
3	Ion Channels (Ion Channel)IBA 01/2022 - 08/2015
3	GlucocorticoidsIBA 06/2020 - 10/2016
3	boldineIBA 01/2020 - 01/2013
3	Coloring Agents (Dyes)IBA 01/2019 - 01/2002
2	Glutamic Acid (Glutamate)FDA Link 02/2021 - 01/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2021 - 06/2007
2	Dexamethasone (Maxidex)FDA LinkGeneric 06/2020 - 10/2016
2	AlkaloidsIBA 01/2020 - 01/2013
2	DysferlinIBA 01/2020 - 01/2016
2	LipopolysaccharidesIBA 10/2019 - 06/2002
2	AntigensIBA 01/2019 - 06/2007
2	InflammasomesIBA 01/2017 - 01/2017
2	Oxygen (Dioxygen)IBA 07/2015 - 09/2009
2	Peptides (Polypeptides)IBA 09/2011 - 02/2010
2	lucifer yellowIBA 12/2010 - 01/2002
2	Ethidium (Ethidium Bromide)IBA 12/2010 - 01/2002
1	Biopolymers (Biopolymer)IBA 01/2022
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Conditioned Culture MediaIBA 01/2022
1	PolyphosphatesIBA 01/2022
1	Glial Fibrillary Acidic ProteinIBA 10/2021
1	CalciumIBA 10/2021
1	Sucrose (Saccharose)IBA 10/2021
1	Apolipoproteins E (ApoE)IBA 02/2021
1	MicroRNAs (MicroRNA)IBA 02/2021
1	Complement C3 (C3 Complement)IBA 02/2021
1	CytokinesIBA 02/2021
1	Complement System Proteins (Complement)IBA 01/2021
1	Cholinergic ReceptorsIBA 01/2020
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2020
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2020
1	Protein Subunits (Protein Subunit)IBA 09/2019
1	Biological ProductsIBA 09/2019
1	Collagen Type III (Type III Collagen)IBA 09/2019
1	thiobarbituric acidIBA 09/2019
1	Immunoglobulin E (IgE)IBA 01/2019
1	Purinergic Receptors (Receptors, Purine)IBA 01/2018
1	IonsIBA 01/2018
1	Neuroprotective AgentsIBA 10/2017
1	Purinergic P2X7 ReceptorsIBA 08/2015
1	Connexin 26IBA 05/2015
1	Protein Isoforms (Isoforms)IBA 01/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014

Therapy/Procedure

6	Denervation 01/2020 - 10/2013
2	Therapeutics 01/2022 - 10/2019
1	Complementary Therapies (Alternative Medicine) 01/2022
1	Drug Therapy (Chemotherapy) 09/2019
1	Ligation 01/2018
1	Punctures 01/2018
1	Transplantation 01/2015